产品货号：
Z14628
中文名称：
FAM120A抗体
英文名称：
Anti-FAM120A Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FAM120A Antibody |
| 指标别名 | C9orf10;DNAPTP1;DNAPTP5;FAM120A;KIAA0183;OSSA;Protein FAM120A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | FAM120A |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | FAM120A antibody was raised against an 18 amino acid synthetic peptide from near the center of human FAM120A.The immunogen is located within amino acids 610 - 660 of FAM120A. |
| 计算分子量 | 122kDa |
| 成分 | FAM120A Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | FAM120A Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | FAM120A (C9orf10) is a member of the constitutive coactivator of PPAR gamma family and the gene was mapped to chromosome 9q22.31.FAM120A was recently detected within the Pur-alpha-containing mRNA-protein complex in the brain.As a novel RNA-binding protein,FAM120A is a critical component of the oxidative stress-induced survival signaling.It may participate in mRNA transport in the cytoplasm.FAM120A activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase.FAM120A protects cells from apoptosis through activation of SRKs in response to oxidative stress.Blocking of the survival signaling mediated by FAM120A,which sensitizes the cancer cells to stress-induced apoptosis,may be a novel therapeutic approach for gastric scirrhous carcinoma cells. |
| Uniprot ID | Q9NZB2 |
| 基因名全称 | Family with sequence similarity 120A |
| 蛋白名全称 | Family with sequence similarity 120A |
| 推荐稀释比 | FAM120A antibody can be used for detection of FAM120A by Western blot at 0.5 ～ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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